Share on Twitter People who participate in arts and craft activities and who socialize in middle and old age may delay the development in very old age of the thinking and memory problems that often lead to dementia, according to a new study published in the April 8, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.People age 85 and older make up the fastest growing age group in the United States and worldwide.“As millions of older US adults are reaching the age where they may experience these memory and thinking problem called Mild Cognitive Impairment (MCI), it is important we look to find lifestyle changes that may stave off the condition,” said study author Rosebud Roberts, MB, ChB, MS, of Mayo Clinic in Rochester, Minn. and a member of the American Academy of Neurology. “Our study supports the idea that engaging the mind may protect neurons, or the building blocks of the brain, from dying, stimulate growth of new neurons, or may help recruit new neurons to maintain cognitive activities in old age.” The study involved 256 people with an average age of 87 who were free of memory and thinking problems at the start of the study. The participants reported their participation in arts, such as painting, drawing and sculpting; crafts, like woodworking, pottery, ceramics, quilting, quilling and sewing; social activities, such as going to the theater, movies, concerts, socializing with friends, book clubs, Bible study and travel; and computer activities such as using the Internet, computer games, conducting web searches and online purchases.After an average of four years, 121 people developed mild cognitive impairment. Participants who engaged in arts in both middle and old age were 73 percent less likely to develop MCI than those who did not report engaging in artistic activities. Those who crafted in middle and old age were 45 percent less likely to develop MCI and people who socialized in middle and old age were 55 percent less likely to develop MCI compared to those who did not engage in like activities. Computer use in later life was associated with a 53 percent reduced risk of MCI.On the other hand, risk factors such as having the APOE gene, having high blood pressure in middle age, depression and risk factors related to blood vessels increased the risk of developing MCI. Pinterest LinkedIn Share on Facebook Email Share
Share on Facebook LinkedIn Share on Twitter Share Pinterest Email For nearly 15 years, Shisheva’s laboratory has studied the cellular functions of two enzymes, PIKfyve and Sac3, and one accessory protein ArPIKfyve – the three proteins originally discovered by her group from 1999 to 2007 – and the role these proteins play in disease mechanisms. Previous work by Shisheva’s team revealed that if the Sac3 enzyme is not bound and protected by ArPIKfyve, it is prone to a quick demise inside the cell. In addition, they found that this double ArPIKfyve-Sac3 protein complex is a part of a bigger, triple assembly incorporating the PIKfyve enzyme as well. The triple complex controls the production and turnover of one rare phospholipid molecule that controls the traffic of membranes towards the digestive system of the cell.It has remained a mystery why the Sac3 mutations are associated with neurodegeneration in humans, whereas the human mutations in PIKfyve are currently linked only to a relatively benign disease of the cornea. This led Shisheva’s team to believe that the double ArPIKfyve-Sac3 complex has separate functions in the brain. Shisheva’s group sought to identify brain-specific proteins that physically interact only with the double complex ArPIKfyve-Sac3.In a recent paper, “The protein complex of neurodegeneration-related phosphoinositide phosphatase Sac3 and ArPIKfyve binds the Lewy-body-associated Synphilin-1 preventing its aggregation,” published online in the Journal of Biological Chemistry, Shisheva and her research team characterized a novel interaction partner of the ArPIKfyve-Sac3 complex in the brain. The Journal of Biological Chemistry is the world’s largest and most cited journal based on PageRank algorithm.“We uncovered that the ArPIKfyve-Sac3 complex binds Synphilin-1, a protein already implicated in the pathogenesis of Parkinson’s disease through its interaction with alpha-synuclein,” said Shisheva. “As alpha-synuclein, Synphilin-1 is also entrapped in the abnormal Lewy body deposits. Our study revealed that the ArPIKfyve-Sac3 complex is an effective inhibitor of aggregate formation by Synphilin-1.”In addition, Shisheva’s team found that excessive levels of Sac3 cause protein self-aggregation and further facilitate the clumping by Synphilin-1. Not surprisingly, researchers in Japan have recently found that excessive Sac3 accumulates in Lewy bodies. Therefore, the ArPIKfyve-Sac3 complex may precipitate Parkinson’s disease manifestation in two ways: when it is too low and when Sac3 is disproportionally high. These observations raise the possibility that increasing the levels of the ArPIKfyve-Sac3 complex may have a beneficial effect in Parkinson’s disease.According to Shisheva, the ArPIKfyve-Sac3 complex could shift Synphilin-1 distribution from a form of multiple aggregates towards the soluble form. Future attempts to block aggregate formation or to break down formed aggregates of Synphilin-1 and, possibly, of alpha-synuclein, based on the ArPIKfyve-Sac3 complex may prove beneficial as a therapeutic approach in reducing neurodegeneration in Parkinson’s disease. The current study provides new insights into the neurodegeneration mechanisms and important clues about novel molecular means for reducing cytoplasmic aggregates in Parkinson’s diseases. More than one million people in the United States are afflicted with Parkinson’s disease, a progressive disorder of the brain that affects movement and coordination. The cause is typically unknown, and presently there is no cure for the disease.Scientists have discovered that the hallmark sign of Parkinson’s disease is the intraneuronal accumulation and progressive spreading of clumps in certain areas of the brain, known as Lewy bodies. These Lewy body inclusions are formed mainly through the accumulation of a protein, called alpha-synuclein. Because of a correlation between the extent of Lewy body clumps and the severity of the Parkinson’s clinical symptoms, it has been largely accepted that these inclusions accelerate the disease process. Therefore, identifying molecules and conditions which decrease or halt the formation of alpha-synuclein-containing toxic inclusions may be beneficial for Parkinson’s disease patients.A research team led by Assia Shisheva, Ph.D., professor of physiology in Wayne State University’s School of Medicine, has made breakthrough advancements on a new molecular mechanism that may provide a means to “melt” these pathological clumps.
Share this:PrintTwitterFacebookLinkedInLike this:Like Loading… Young people from across the Region will have an opportunity to interact with the CARICOM Secretary General Ambassador Irwin LaRocque via social media on 29 June 2015. The event, which is happening just before the Thirty Sixth Meeting of the Conference of Heads of Government of CARICOM in Barbados, is an initiative of the CARICOM Youth Ambassadors. Join the conversation by using the hashtag #askSG on Twitter, Facebook and Instagram. Persons can share their questions and comments via any of these media, which will be monitored by the CYAs. The Secretary General will be available from 6:00 pm to 8:00 pm to answer questions and host a discussion with the participating youngsters. The main topic of discussion will be ‘Entrepreneurship: CARICOM’s Economic Life-jacket’. According to Kishore Shallow, Vice Dean of Communications for the CARICOM Youth Ambassadors, many scholars share the view that entrepreneurship is the key to solving the problem of unemployment which is a major challenge for CARICOM countries. He said he thinks entrepreneurship could provide a major boost for CARICOM economies, and reduce the strain on governments, which could then divert more energy and resources to other critical areas such as health and education One of the main objectives of the social media interaction is to expose young people across the Region to the work of the CARICOM Secretariat and its organs. It also aims to highlight the strides made by the CARICOM Secretariat in the area of youth engagement and development. It will also allow the Secretary-General to share his opinion on entrepreneurship and give the average young person a chance to “interact” with him while sharing their views and opinions on CARICOM-related issues. This is not the first social media interaction with youth and the CARICOM Secretary-General. More than 37 000 hits were received from users of the CARICOM Youth Ambassadors Facebook page from one held in January 2014. It was hosted at the Secretariat’s headquarters in Georgetown, Guyana, and its purpose was to expose young people across the Region to the work of the CARICOM Secretariat and its organs. The forum was hosted in two parts. The first was spearheaded by Assistant Secretary-General in charge of Human and Social Development, Dr. Douglas Slater. Issues related to the CARICOM Youth Development Action Plan, which was developed to guide national policy, integrated planning and action regarding youth, were discussed. Shallow said the CYA’s chose to have another social media interaction with the CARICOM Secretary-General for young people because they have realised its value in sensitising them about topical issues in the Region, as well as to share and to receive feedback. It is hoped that this one will receive even more attention from the youth than the one last year. CARICOM SG’s social media interaction with youths a successYouth from across the Region as well as the Caribbean Community (CARICOM) diaspora Monday evening got the opportunity to engage in a live social media interaction with the CARICOM Secretary General Ambassador Irwin LaRocque from 6:00 pm-8:00 pm. The event was hosted just before the Thirty-Sixth Meeting of the Conference of…June 30, 2015In “Anguilla”Social Media Interaction with CARICOM SG today Young people from across the Region will this evening be able to interact with CARICOM Secretary-General Ambassador Irwin LaRocque between 6 and 8pm. The event, which is happening just before the Thirty-Sixth Meeting of the Conference of Heads of Government of CARICOM in Barbados, is an initiative of the CARICOM Youth…June 29, 2015In “Barbados”#AskSG876 about role of youth in advancing Single MarketYouth across the CARICOM Region will, once again, have an opportunity to interact with the CARICOM Secretary-General, Ambassador Irwin LaRocque, via social media on Monday, 2 July. The interaction begins at 4:30 pm in Jamaica, 5:30 pm in ECT, 3:30 pm in Belize, and 6:30 pm in Suriname. The main topic of…July 1, 2018In “Associate Member States”Share this on WhatsApp
Up Next:Phil Moore Joins Federated Auto Parts Distributors In this article: Print FARMINGTON HILLS, MI — GDX Automotive has appointed Howard Duxbury as COO and president, global. Duxbury came to GDX Automotive after senior management positions with TI Automotive and Siebe Automotive. AdvertisementClick Here to Read MoreAdvertisement “GDX is fortunate to have a proven automotive industry leader of Duxbury’s qualifications joining the team as we concentrate our efforts on improving operational performance of our global businesses,” said David Thursfield, GDX Automotive executive chairman. In addition to Duxbury’s appointment, GDX also announced the appointments of several senior executives who will report to Duxbury: Janice Stipp, executive vice president, administration and CFO. Stipp’s previous experience includes serving as finance director at TI Automotive Global Fuel Systems and vice president, finance of Oxford Automotive. Doug Chapple, president, North America. Chapple joined GDX Automotive in March 2005 after leading Sarnamotive Blue Water Inc., a supplier of injection molded plastic components. Mark Ploof, managing director, International Operations. An adviser to Cerberus Capital Management, has previous industrial restructuring and operational experience with General Electric. Ploof succeeds Mark Krupp in this position. Mark Krupp, vice president, North America special projects with responsibility for operational restructuring. For more information about GDX Automotive, visit: gdxautomotive.com. _______________________________________ Click Advertisement Don’t Miss:Cooper Names New VP, Global Supply Chain
Colonel Leonard Waterworth, Executive Director of the Port of Houston Authority, announced last week that he is stepping down as its Executive Director.Waterworth advised the Port Commission that he had accepted the role for two years, to help the Port Authority through recent transitions and to use his U.S. Army Corps of Engineers background to help obtain permits to deepen and widen the Port Authority’s container terminal channels. Having completed those matters, he advised that he wanted to pursue other opportunities, including personal travel.In making his announcement at the Port Commission meeting, he stated: “I take pride in our accomplishments on my two year anniversary with the Port Authority. I knew I could provide leadership stability during a transitional period for the Port Authority, but as a team we have achieved so much more.”He said: “Under the combined leadership of the Port Commission and management, the Port Authority has increased revenues and profitability to record levels. We obtained the first long-term commitments with two cruise lines to use the Bayport Cruise Terminal for its intended purpose. And, maybe most importantly, working with the Army Corps of Engineers, we are on the verge of obtaining the necessary permits to prepare our container terminals for the larger ships we will see from the Panama Canal expansion, and we achieved this objective in about half the expected time.”Waterworth continued: “I have been proud to lead the capable staff at the Port Authority, and to work in tandem with the Port Commission. I thank Commissioners for the opportunity to serve, and thank the staff for their dedicated work on behalf of the Port Authority, the premier economic engine for our region.”Janiece Longoria, Chairman of the Port Commission, congratulated Waterworth on his service: “My fellow Port Commissioners and I are grateful to the Colonel for his steady leadership and his service to the Port Authority during his tenure. He worked effectively on many endeavors including operational matters and the federal permit to deepen and widen the Bayport and Barbours Cut Channels. We are proud of what has been accomplished during the past two years, and the Port Commission wishes Len the very best in his future endeavors.”The Chairman further announced that the Port Commission has appointed Roger Guenther, Deputy Executive Director of Operations, as the Port Authority’s Executive Director, and said: “Given his background and experience, the growth in our business under his operational leadership, and his long and positive service for the Port of Houston Authority, we are confident that Mr. Guenther is the right choice as successor to lead the institution as we move forward.”[mappress]Press Release, February 5, 2014
Ships agency services and maritime logistics had been provided in Japan by Wilhelmsen Aall Ships Service and these will combine with the full range of services offered by Wilhelmsen Ships Service to give a seamless continuity to customers under the new Wilhelmsen Ships Service banner across the region.Neal de Roche, area director North East Asia explains the process. “A management restructure during 2008 moved Wilhelmsen Aall Ships Service considerably forward” he said. “Customer feedback over the next couple of years was very positive and the company gained considerable market share in that period.”Wilhelmsen Ships Service then took steps to acquire 100 percent ownership of Wilhelmsen Aall Ships Service, with the objective of accelerating the combination of resources and business opportunities within the existing Wilhelmsen Ships Service entities already in Japan.De Roche adds “It has always been our priority to ensure we operate with daily Wilhelmsen Ships Service values, governance and policies. This acquisition will allow us to move at a faster pace in aligning ourselves with the overall strategy and vision we have for the future in the region.”
Berard Transportation moved the 80 m x 18 m vessel from its position in a fabrication yard to the drydock in preparation for launch.Challenging weather conditions and nearly a week’s worth of rain made ground conditions very poor. Upon Polaris’ arrival at the drydock, Berard rotated the vessel by 90 degrees in preparation for the load-out. Then the drydock’s water pumps were activated and the load slid forward to its final position, ready to be discharged into the water. www.berardtrans.com
CES and its UK distributor, Shad Group, presented the VRS-K, which boasts a lifting capacity of 150 tonnes, to CS Wind at its newly developed offshore wind turbine tower manufacturing plant in Campbeltown, Scotland.CS Wind is utilising the pair of reachstackers for handling wind tower components. The new equipment was demonstrated with the lift and move of a 111-tonne wind tower section across the facility (pictured below). The new VRS-K heavy-duty reachstacker joins CES’s VRS-J and VRS-L models, which offer 120-tonne and 250-tonne lifting capacities respectively.Nicolas Huthloff, managing director of CES Group, said the new reachstacker is an industry first, not just due to its high lifting capacity but also its variable telescopic wheelbase, which allows for up to seven different wheelbases and capacities in one machine.”The sliding, extending chassis keeps ground pressure very low,” added Peter Doggett, managing director of Shad Group. “This is a major investment on the part of CS Wind and the operations here will not work without these machines… The reachstackers have been designed from the ground up and CS Wind is the first customer in the world.”Huthloff added: “We do see a growing demand in heavy-duty reachstackers. Currently you must use self-propelled modular transporters (SPMT) and crawler cranes to lift and move weights more than 130 tonnes. Investment is far higher for two crawler cranes and SPMTs, in comparison to two reachstackers, so the customer can save a lot of costs.”Huthloff has also identified the oil and gas and steel industries as target markets for the VRS reachstacker range.Doggett also said that the reachstackers are more reliable and cheaper to maintain than using a combination of crawler cranes and SPMTs.According to Dong Energy, which made a multi-million dollar investment in CS Wind’s new offshore tower manufacturing facility, the new location will be able to produce at least 50 towers a year for the UK’s burgeoning wind energy industry. CES presents the reachstackers to CS Wind. www.cesgroup.euwww.cswinduk.comwww.shadgroup.co.ukwww.dongenergy.com
The Crown Prosecution Service has taken the unusual step of clarifying how it makes charging decisions after being heavily criticised for pressing ahead with a case against TV presenter Caroline Flack, who died on Saturday.In December the 40-year-old host of reality TV show Love Island was charged with assault after allegedly attacking her boyfriend at her home. Flack pleaded not guilty and a trial was due to take place next month. However, on Saturday her family said she died.The news prompted widespread criticism of the way Flack has been treated in the media since the alleged incident and the CPS’s decision to prosecute her.A CPS spokesperson said: ‘Our deepest sympathies go to the family and friends of Caroline Flack. Given the tragic circumstances, we will not comment on the specifics of this case at this stage.’However, yesterday the prosecuting body posted a detailed explanation of how it decides whether to charge an individual with a criminal offence.The CPS said it had to review every case referred by the police and applied the same two-stage test to every charging decision: does the evidence provide a realistic prospect of conviction and is it in the public interest to prosecute?Guidance for prosecutors when considering domestic abuse allegations gives specific advice on how to proceed when a complainant does not want to support a prosecution ‘which can often be a feature of these difficult cases’. Guidance was recently published for prosecutors in cases involving suspects or defendants with mental health conditions or disorders.
THE CHAIRMAN of Pakistan’s Railway Board Kurshid Ahmad Khan joined ceremonies at Lahore station on January 15 to dispatch the first cross-border train to India for more than two years. The Samjhauta Express between Lahore and Delhi had been discontinued in 2001.A three-year agreement to restore freight and passenger services was signed by representatives from the two railways at a two-day conference in Delhi on December 18-19. The passenger service will initially operate twice a week between Lahore and Attari, from where Indian Railways will provide connecting services to Amritsar, Delhi, Kanpur, Lucknow, Aligarh, Ilahabad, Saharanpur and Muradabad. Under the agreement, PR will be allowed to open its own ticket offices in the eight cities.PR General Manager Mohammad Iqbal Khatri expected cross-border freight services to resume a few days later.
HELLENIC RAILWAYS has called bids for detailed engineering design on the first phase of the proposed rail network intended to open up the western side of the country. Under an agreement signed by former Transport Minister Christos Verelis and EU Transport & Energy Commissioner Loyola de Palacio, the Western Railway Axis has been included in the list of TEN priority projects which will receive EU funding in 2006-14.The Western Railway comprises two main corridors. One will run west from the existing OSE terminus at Kozani through Kalambaka to Ioannina and Igoumenitsa on the Ionian Sea coast opposite Kerkyra (Corfu). The other will run south from Ioannina to Andírrion where it will cross the Gulf of Patros to the Peleponnese, where it will continue through Patras and Pyrgos to Kalamata on the south coast.The Greek government has committed to start work on the east-west route in 2006 for completion by 2012. The north-south corridor will follow in 2008 and should be finished by 2014.Plans have already been approved for the Kozani – Kalambaka – Ioannina – Igoumenitsa route, together with a branch from Siatista to Kastoria. Detailed alignments, preliminary technical work and geotechnical surveys have already begun, and the next step will be to complete an environmental impact assessment.To meet the deadlines agreed with the EU, the government decided earlier this year to push ahead with appointing consultants to undertake engineering design on the first phase. According to the official OJEU notice, this work is worth €21m. Meanwhile, preliminary design and geotechnical studies are getting underway for Phase B, together with hydraulic studies for the various tunnels. Work is also in hand to select locations and design station structures.
MEXICO: Ferromex has awarded Alstom a five-year contract to maintain 219 EMD and GE diesel freight locomotives The contract announced on January 9 includes condition-based and predictive maintenance which will include oil and vibration analysis and remote monitoring. This is expected to bring a reduction in operating costs. The locomotives will be maintained at Ferromex depots in Torreón, Chihuahua and Guadalajara, supporting 150 jobs directly.
Nigeria’s floating school: Eco-friendly school changing lives in Makoko slumLocated in one of Nigeria’s biggest informal settlements, the Makoko Floating School is an innovative new building that can house up to 100 students and teachers.The pyramid-shaped structure is buoyed by over 200 plastic barrels and is able to withstand tidal changes and extreme weather patterns.Nigeria’s floating school: Eco-friendly school changing lives in Makoko slumThe 100-year-old slum is home to thousands of people whose major source of income is fishing, sand harvesting and timber tradingNicknamed the Venice of Lagos, Nigeria’s Makoko slum is home to nearly 100,000 people.Residents, who are mostly fishermen, live on stilts in the lagoon and move between their houses by canoe.47 students currently study here. The Floating School offers free education but receives funding from donors.Makoko was designated for demolition in 2013 which would have left many homeless.Most residents in the slum are migrants from other countries in West Africa trying to make a living in Nigeria.Majority of Lagosians live in what are effectively slums with no reliable electricity or water.Projects like Makoko’s Floating School are helping to address some of the growing challengesof climate change and urbanization that people here face.CCTV’S Maria Galang with this report.
Tanzania has banned the use of plastic bags, effective from January 2017.The East African country’s authorities have advised manufacturers of the paper bags to adopt new technologies of making biodegradable bags.“Plastic bags will not be used in the country from January 1,” Luhaga Mpina, the Deputy Minister in the Vice-President’s Office responsible for Environment, told a Parliamentary Committee on Industries, Trade and Environment on Friday.The minister presented a raft of regulations in line with the ban, indicating that there will be an exemption of the use of plastic bags in medical services, industrial packaging, construction industry, agricultural sector and in sanitary use and waste management.Neighbouring Rwanda already has a plastic ban in place, and this is said to be one of the major reasons for Kigali’s cleanliness.
Tanzania builds another school to protect albino children Somalia drought forcing children out of school KPALONG, TAMALE, NORTHERN GHANA, GHANA – 2018/02/10: A group of children are seen posing in their classroom for a photo in the remote village of Kpalong.Kpalong is 50kms outside Tamale in Northern Ghana. (Getty Images) KPALONG, TAMALE, NORTHERN GHANA, GHANA – 2018/02/10: A group of children are seen posing in their classroom for a photo in the remote village of Kpalong.Kpalong is 50kms outside Tamale in Northern Ghana. (Getty Images)A global charity initiative has been supporting the government of Ghana in increasing school enrollment for children across the country, an official said Friday.With support from other partners, the Ghana chapter of Plan International (Plan International Ghana), a child and gender-based charity, has been running a five-year program to promote school enrollment in poor and deprived communities, its Country Director Solomon Tesfamariam said.The Reaching and Teaching Out of School Children is a five-year program spanning from 2015 to 2020, aiming to enroll 90,000 out-of-school children from five regions.The project advocates that partners at the national and district levels urgently address a lack of schools in communities where there were none.Available data indicate that Ghana’s school enrollment rate stood at 84 percent by 2013.“The project will enroll boys and girls in the beneficiary regions through the Complementary Basic Education, and transition 70 percent of the graduates to formal primary schools,” Tesfamariam said at the One Day West African Corporate Social Responsibility Conference.He said the program ultimately aims at ensuring universal school enrollment in the West African country where education accounts for about 23 percent of annual state expenditure.Related Kenya introduces digital learning tools to school going children
(Antigua Observer) There is a slight reduction in the number of criminal matters that were reported to the Royal Police Force of Antigua and Barbuda for the first quarter of 2018. However, the police are still concerned about an increase in traffic accidents and fires.The statistics were shared with reporters during a news conference held at the Police Headquarters Tuesday morning.According to Atley Rodney, Acting Commissioner of Police, during the period of January 2017 to April 2017, 900 crimes were reported to the police, while 707 were reported so far for January to April 2018.These offences include: break-in, attempted break-in, burglary, break-in and larceny, larceny, praedial larceny, wounding, assault, murder, attempted murder, attempted suicide, suicide, malicious damage, rape, attempted rape, buggery, indecent assault, indecent exposure, unlawful sexual intercourse, serious indecency, incest, and arson among others.“There were general examples in most areas, such as larceny, 84 less at this time; break-in and larceny, 20 less; indecent assault, eight less than last year. There were slight increases in certain crimes which are of concern to the police. These include murder moving from four for this same period last year to six this year and two additional cases of rape,” Rodney said.Rape increased from seven in the first four months of 2017 to nine, so far, in 2018.Praedial larceny jumped from five in 2017 to 16 reports for the first four months this year.Meanwhile, the traffic department recorded a total 770 vehicular accidents in the first four months of 2017 and three road fatalities and so far, this year, 926 accidents with one fatality have been reported..“This increase is not only within the city limits but the out districts. We have to appeal to the drivers to be more careful and to respect the rules of the road. The police are taking measures to address this trend,” Rodney told reporters, adding that the numbers are increasing despite an increase in public education.The Fire Department also had its hands full for the period January to April 2018. It responded to 83 fires – 46 were bush fires, 25 house fires and 12 involved vehicles.Around this same period last year, a total of 65 fires were recorded – 41 bush fires, 13 vehicular fires and 11 house fires.At the start of the year, Head of the Traffic Department Inspector Elson Quammie noted that several measures would be taken to reduce the number of accidents recorded annually, including the arrest and the revocation of driver’s licenses.Acting Commissioner Rodney said these measures will be continued throughout the rest of the year. NewsRegional Antigua reports decrease in crime by: – May 16, 2018 Tweet Share Share Sharing is caring! 46 Views no discussions Share